You have left out several important pieces of information.
What skis will the bindings be put on? Length?
How do you ski?
Where do you ski?
Does your ski have a riser or will the binding be flat on the top of the ski?
I assume you aren't including the ski in the heights you mention.
In general a high stack height is beneficial on a narrower ski to increase your ability to hold an edge and to keep your boot from hitting the snow when you are at high edge angles. A wider ski, 75 mm plus, won't benefit from the high stack height.
The delta between toe and heel is definitely going to affect your skiing as it will effectively modify the forward lean of your boot, thus how you stand over your skis and can balance fore and aft, among other things.