I once drove from Washington DC to Hunter, NY, which takes like eight hours to ski on something like 10 trails. I was jonesing in a huge way!
I've driven from DC to Stowe, Vermont, but that was for 3 days of skiing.
drives have been from Boston to the White Mountain regions in Friday night snowstorms. The 140 mile trip from my door to Lincoln, NH has taken me 7+ hours. The next day has always been amazing though.
I had a really memorable drive from DC to Canaan Valley / Timberline in West Virginia in a snowstorm one year. That was like a 6 hour, 140 mile trip. The roads to Canaan (rhymes with "insane") aren't exactly major highways, and they aren't really straight, or flat. I am amazed to this day that my little front-wheel-drive Mazda Protege with all-season tires survived that trip. Good skiing that weekend though.