good advice from ssh in his response.!
Most binding brands have their adherents and the Look/Rossi followers on this board are undoubtedly the most vocal. Personally I have never much liked them as I have never felt confident that they are properly engaged when you step in although I am the fisrst to admit this goes back to some of the earlier models (inclusing the original Ess/Look Nevada) rather than the current crop. Also unimpressed with the quality when I found all 4 springs had actually broken in half on a pair of Look 99RS after one season. But, as with so many other views here these are simply personal opinions.
I skied Markers for several years with no problems and have used Salomons for over 30 years. My 1080s with the 912 TI and my 3V slalom race with 914s have not experienced the toe screws loosening on either pair. This does not mean it will not happen but I haven't seen it yet.
I also started using Tyrolias on my Race GS and another pair of skis this year for the first time. I had reservations about them in the past beacause of the reports of difficulty getting into the diagonal heel. I have not found any problem with this and have been very impressed with them.
So, to get back to the point and to agree with ssh, there are very few poor bindings out there, most perform really well with some differences in characteristics between brands. Pick one that you trust, that fits the ski, and you get a good deal on. (And if you like Marker I have a brand new pair of 9.2 Race EC14 for sale!