I happened to notice that Hotwire seems to have greatly increased their fees for booking "Hot Rate" hotels.
The result is that their advertised per night rates can be minimally beneficial to more expensive than competing sites.
An example: Teton Village from 1/18/16 until 1/22/16 on Hotwire "Hot Rate" for a 4.5 star hotel, boutique, slopeside (so the hotel is either Teton Mountain Lodge or Hotel Terra) quoted rate: $236/night. However upon making it to check out the total is $1,571, not including the resort fee, for a total of $314 a night.
Checking the same dates on Trivago, and choosing Hotel Terra I was routed to Priceline and given this amount:
In other words, the Priceline choice, where you know you are getting Hotel Terra for sure is a 3.4% discount to Hotwire's rate! Not a huge difference overall, but I certainly have soured to Hotwire's rates. I booked through Hotwire last year and did not see anything like this. Anecdotally I have noticed that the fees Hotwire charges seem to change, but I don't have visual proof of this.
I hope this is helpful as the flakes start flying and people are searching for deals.